Based on the panel data of 15 prefecture-level cities in Anhui Province from 2004 to 2019,the industrial structure transformation effect of the policy of undertaking industrial transfer demonstration area in Wanjiang City belt is analyzed by using the differential-in-differentials model.?The results show that the establishment of the demonstration area significantly inhibits the upgrading of regional industrial structure, but it has no significant effect on the rationalization of industrial structure.?The influence of demonstration area on regional industrial structure is mainly reflected by promoting the development of secondary industry.?Finally, in order to promote the demonstration area to play a demonstrative role in undertaking industrial transfer, relevant policy suggestions are put forward.