Abstract:Based on the panel data of 30 provinces and autonomous regions from 2008 to 2016, empirically studies the impact of business environment on innovation performance of high-tech industry by using fixed effect model. The regression results show that: business environment has a significant positive impact on the number of high-tech industry patent applications, and the impact on the western region is significantly greater than that in the eastern and central regions, but the impact intensity is lower than R & D internal expenditure, the number of scientific research institutions and other factors; from the national level, the improvement of business environment has a negative impact on the sales revenue of new products in high-tech industry. According to the regression results,government should further promote the healthy development of high-tech industry by strengthening the protection of intellectual property rights and strict examination and approval standards of high-tech industry.